Kenzo Iizuka Selected Research

Deoxycytidine

1/2019	Two phase I, pharmacokinetic, and pharmacodynamic studies of DFP-10917, a novel nucleoside analog with 14-day and 7-day continuous infusion schedules.
10/2018	Phase II study of DFP-10917, a deoxycytidine analog, given by 14-day continuous intravenous infusion for chemotherapy-refractory advanced colorectal cancer.
3/2018	Analysis of the prolonged infusion of DFP-10917, a deoxycytidine analog, as a therapeutic strategy for the treatment of human tumor xenografts in vivo.

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Kenzo Iizuka Research Topics

Disease

5	Neoplasms (Cancer) 12/2020 - 01/2017
2	Ovarian Neoplasms (Ovarian Cancer) 03/2018 - 01/2018
2	Body Weight (Weight, Body) 03/2018 - 01/2017
1	Gallbladder Neoplasms (Gallbladder Cancer) 12/2020
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 12/2020
1	Diarrhea 01/2019
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2019
1	Vomiting 01/2019
1	Abdominal Pain (Pain, Abdominal) 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 10/2018
1	Leukemia 03/2018
1	Ascites 01/2018
1	Thrombocytopenia (Thrombopenia) 01/2017

Drug/Important Bio-Agent (IBA)

4	DFP-10917IBA 01/2019 - 03/2018
3	DeoxycytidineIBA 01/2019 - 03/2018
2	DFP-11207IBA 12/2020 - 01/2017
2	Fluorouracil (Carac)FDA LinkGeneric 12/2020 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 03/2018 - 01/2018
2	Pharmaceutical PreparationsIBA 03/2018 - 01/2018
1	Capecitabine (Xeloda)FDA Link 12/2020
1	A 7 (A-7)IBA 01/2019
1	A-Form DNA (A-DNA)IBA 03/2018
1	Cytarabine (Cytosar-U)FDA LinkGeneric 03/2018
1	CytosineIBA 03/2018
1	Gemcitabine FDA Link 03/2018
1	NucleosidesIBA 03/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	Thymidylate SynthaseIBA 01/2018
1	DFP-10825IBA 01/2018
1	LuciferasesIBA 01/2018
1	Liposomes (Liposome)IBA 01/2018
1	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 01/2017
1	Orotate PhosphoribosyltransferaseIBA 01/2017

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 12/2020 - 10/2018
2	Intravenous Infusions 01/2019 - 10/2018